Home / Models / Qwen2.5 0.5B Instruct / NVIDIA RTX 4080 16 GB
Can Qwen2.5 0.5B Instruct run on NVIDIA RTX 4080 16 GB?
Yes. Calculated memory fit: Qwen2.5 0.5B Instruct can run entirely in this GPU’s usable VRAM at one or more supported quantizations.
Can it run?
- Can it run?
- Yes, full GPU fit (calculated estimate).
- Full GPU fit?
- Yes
- Model
- Qwen2.5 0.5B Instruct · 494M
- GPU
- NVIDIA RTX 4080 16 GB · 16 GB advertised
Memory calculation
Breakdown for Q4 at 8K context, batch size 1. Calculator v1.0.0.
| Model weights | 0.3 GB |
|---|---|
| KV cache | 0.1 GB |
| Runtime reserve | 0.5 GB |
| Safety margin | 0.3 GB |
| Required (estimated) | 1.2 GB |
| GPU usable VRAM | 14.4 GB |
Result: FITS IN VRAM
Quantization table
| Quantization | 2K | 4K | 8K | 16K | 32K |
|---|---|---|---|---|---|
| BF16 | Fits | Fits | Fits | Fits | Fits |
| FP16 | Fits | Fits | Fits | Fits | Fits |
| Q3 | Fits | Fits | Fits | Fits | Fits |
| Q4 | Fits | Fits | Fits | Fits | Fits |
| Q5 | Fits | Fits | Fits | Fits | Fits |
| Q6 | Fits | Fits | Fits | Fits | Fits |
| Q8 | Fits | Fits | Fits | Fits | Fits |
What fits entirely in VRAM?
- BF16 at 16K context
- BF16 at 2K context
- BF16 at 32K context
- BF16 at 4K context
- BF16 at 8K context
- FP16 at 16K context
- FP16 at 2K context
- FP16 at 32K context
- FP16 at 4K context
- FP16 at 8K context
- Q3 at 16K context
- Q3 at 2K context
What requires RAM offload?
Offload is shown only when the model does not fully fit in usable VRAM but stays within the modeled offload allowance.
Available graphics cards
These SKUs use this GPU chip. Amazon CTAs appear only for EXACT/HIGH matches. Absence of a price does not change the compatibility result above.

MSI VENTUS RTX 4080 16GB 3X OC NVIDIA GeForce RTX 4080 GDDR6X
16 GB · Amazon EXACT
$1750.00
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GIGABYTE GAMING GeForce RTX 4080 16GB OC NVIDIA GDDR6X
16 GB · Amazon EXACT
$1799.00
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MSI GAMING GeForce RTX 4080 16GB X TRIO NVIDIA GDDR6X
16 GB · Amazon EXACT
$1689.00
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ASUS ROG -STRIX-RTX4080-O16G-GAMING NVIDIA GeForce RTX 4080 16 GB GDDR6X
16 GB · Amazon EXACT
$1699.95
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GIGABYTE EAGLE GeForce RTX 4080 16GB OC NVIDIA GDDR6X
16 GB · Amazon EXACT
$859.99
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GIGABYTE AERO GeForce RTX 4080 16GB OC NVIDIA GDDR6X
16 GB · Amazon EXACT
$1799.00
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ASUS ROG -STRIX-RTX4080-O16G-WHITE NVIDIA GeForce RTX 4080 16 GB GDDR6X
16 GB · Amazon EXACT
$1998.97
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GIGABYTE EAGLE GV-N4080EAGLE-16GD graphics card NVIDIA GeForce RTX 4080 16 GB GDDR6X
16 GB · Amazon EXACT
$1699.00
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GIGABYTE AORUS GeForce RTX 4080 MASTER NVIDIA 16 GB GDDR6X
16 GB · Amazon EXACT
$1499.97
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GIGABYTE AORUS XTREME AORUS GeForce RTX 4080 16GB XTREME WATERFORCE NVIDIA GDDR6X
16 GB · Amazon EXACT
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ASUS TUF Gaming TUF-RTX4080-O16G-GAMING NVIDIA GeForce RTX 4080 16 GB GDDR6X
16 GB · Amazon unmatched

ASUS TUF Gaming TUF-RTX4080-16G-GAMING NVIDIA GeForce RTX 4080 16 GB GDDR6X
16 GB · Amazon unmatched
Sources
Model: official config Qwen/Qwen2.5-0.5B-Instruct (main). GPU/product specs: Icecat. Compatibility: RigForAI calculator v1.0.0 estimated VRAM · Q8 at 8K: FITS_IN_VRAM. Amazon: affiliate commerce match, not a spec source.
