Home / Models / Mistral Nemo 12B Instruct / NVIDIA RTX 4080 16 GB

Calculated memory fit · performance is a separate section

Can Mistral Nemo 12B Instruct run on NVIDIA RTX 4080 16 GB?

Yes. Calculated memory fit: Mistral Nemo 12B Instruct can run entirely in this GPU’s usable VRAM at one or more supported quantizations.

Can it run?

Can it run?
Yes, full GPU fit (calculated estimate).
Full GPU fit?
Yes
Model
Mistral Nemo 12B Instruct · 12B
GPU
NVIDIA RTX 4080 16 GB · 16 GB advertised

What else can NVIDIA RTX 4080 16 GB run? · Find other GPUs for Mistral Nemo 12B Instruct

Memory calculation

Breakdown for Q4 at 8K context, batch size 1. Calculator v1.0.0.

Model weights7.2 GB
KV cache1.3 GB
Runtime reserve0.9 GB
Safety margin0.5 GB
Required (estimated)9.7 GB
GPU usable VRAM14.4 GB

Result: FITS IN VRAM

Quantization table

Quantization2K4K8K16K32K64K128K
BF16OffloadOffloadOffloadOffloadOffloadOffloadOffload
FP16OffloadOffloadOffloadOffloadOffloadOffloadOffload
Q3FitsFitsFitsFitsFitsLimited contextLimited context
Q4FitsFitsFitsFitsFitsLimited contextLimited context
Q5FitsFitsFitsFitsLimited contextLimited contextLimited context
Q6FitsFitsFitsFitsLimited contextLimited contextLimited context
Q8OffloadOffloadOffloadOffloadOffloadOffloadOffload

What fits entirely in VRAM?

What requires RAM offload?

Offload is shown only when the model does not fully fit in usable VRAM but stays within the modeled offload allowance.

Performance

Separate from memory fit. Runtime is llama.cpp · quantization bucket Q4 (GGUF Q4_0 maps to Q4). Workload is llama-bench pp512 / tg128 (short context, batch 1, full GPU offload). This is not a ranking and not a 8K–128K speed claim.

Model
Mistral Nemo 12B Instruct
GPU
NVIDIA RTX 4080 16 GB
Runtime
llama.cpp · CUDA · model 1.0.0
Decode
~71 tok/s · Calibrated estimate · MEDIUM confidence (spread ~63 tok/s–~80 tok/s)
Prefill
~5086 tok/s at a 512-token prompt · Calibrated estimate · MEDIUM confidence
Time to first token
~101 ms for a 512-token prompt (512 / prefill tok/s). Not estimated at 8K–128K.

decode_tps = GPU_efficiency × memory_bandwidth / model_weight_bytes; efficiency from same-gpu Llama 2 7B Q4_0 efficiency

Performance methodology · Performance explorer

Available graphics cards

These SKUs use this GPU chip. Amazon CTAs appear only for EXACT/HIGH matches. Absence of a price does not change the compatibility result above.

Check price on Amazon

Sources

Model: official config mistralai/Mistral-Nemo-Instruct-2407 (main). GPU/product specs: Icecat. Compatibility: RigForAI calculator v1.0.0 estimated VRAM · Q8 at 8K: CPU_RAM_OFFLOAD_REQUIRED. Amazon: affiliate commerce match, not a spec source.